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CLINICAL STUDIES

Islets Allotransplantation for patients with T1DM

Islets Autotransplantation for patients with T1DM

Kidney transplantation

OPEN ENROLLMENT

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Mercury.

A Phase 3 Prospective, Randomized, Multi-center, Open-label, Controlled Trial to Assess the Efficacy and Safety of Cellular Immunotherapy with MDR-101 for Induction of Immune Tolerance in Recipients of HLA-matched, Living Donor Kidney Transplants

Funded by Medeor Therapeutics, Inc

OPEN ENROLLMENT

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A randomized double-blind placebo-controlled study to evaluate the efficacy and safety of CINRYZE® (C1 esterase inhibitor [human]) for the treatment of acute antibody-mediated rejection in kidney transplant patients.

Funded by Shire ViroPharma, Inc..

OPEN ENROLLMENT

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A Phase 2a, Randomized, Open-Label, Active Control, Multi-Center Study to Assess the Efficacy and Safety of Bleselumab in

Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de novo Kidney Transplant Recipients.

Funded by Astellas Pharma Global Development, Inc.

COMPLETED

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A Phase 2a, Randomized, Open-Label, Active Control, Multi- Center Study to Assess the Efficacy and Safety of ASKP1240 in de novo Kidney Transplant Recipients

Funded by Astellas Pharma Global Development, Inc.

COMPLETED

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A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ from a CMV-Seropositive Donor.

Funded by Astellas Pharma Global Development, Inc.

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